| Product name | LIFR Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human LIFR |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse, |
| Applications | WB,ELISA,IHC |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | LIFR; Leukemia inhibitory factor receptor; LIF receptor; LIF-R; CD118 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 120kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | LIFR encodes leukemia inhibitory factor receptor alpha that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. |
| Gene ID | 3977 |
| Alternative | LIFR; Leukemia inhibitory factor receptor; LIF receptor; LIF-R; CD118 |
| Others | LIFR Polyclonal Antibody detects endogenous levels of LIFR protein. |
| Accession | P42702 |
| Observed Band(KD) | 120 |
Fig. Western Blot analysis of 293 cells using LIFR Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.
You must be logged in to post a review.
Reviews
There are no reviews yet.