| Product name | KIRR2 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human KIRR2 protein |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Kin of IRRE-like protein 2; Kin of irregular chiasm-like protein 2; Nephrin-like protein 3 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 77kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | KIRREL2 gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter. |
| Gene ID | 84063 |
| Alternative | Kin of IRRE-like protein 2; Kin of irregular chiasm-like protein 2; Nephrin-like protein 3 |
| Others | The antibody detects endogenous levels of KIRR2 protein |
| Accession | Q6UWL6 |
| Observed Band(KD) | 77 |
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