| Product name | ITBP1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human ITBP1 protein |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Integrin beta-1-binding protein 1; Integrin cytoplasmic domain-associated protein 1; ICAP-1 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 22kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The cytoplasmic domains of integrins are essential for cell adhesion. The Integrin Subunit Beta 1 Binding Protein 1 encoded by ITGB1BP1 binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. |
| Gene ID | 9270 |
| Alternative | Integrin beta-1-binding protein 1; Integrin cytoplasmic domain-associated protein 1; ICAP-1 |
| Others | The antibody detects endogenous levels of ITBP1 protein |
| Accession | O14713 |
| Observed Band(KD) | 22 |
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