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IRK13 Polyclonal Antibody

IRK13 Polyclonal Antibody

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Specification

Product name IRK13 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human IRK13 protein
Host Rabbit
Reactivity Human,Rat,Mouse,
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Inward rectifier potassium channel 13; Inward rectifier K(+) channel Kir7.1; Potassium channel, inwardly rectifying subfamily J member 13

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 39kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background KCNJ13 (Potassium Voltage-Gated Channel Subfamily J Member 13) is a Protein Coding gene. Diseases associated with KCNJ13 include Snowflake Vitreoretinal Degeneration and Leber Congenital Amaurosis 16. Among its related pathways are Collagen chain trimerization and Dopamine-DARPP32 Feedback onto cAMP Pathway. KCNJ13 encodes a member of the inwardly rectifying potassium channel family of proteins. Members of this family form ion channel pores that allow potassium ions to pass into a cell. The encoded protein belongs to a subfamily of low signal channel conductance proteins that have a low dependence on potassium concentration. Mutations in KCNJ13 are associated with snowflake vitreoretinal degeneration. Alternate splicing results in multiple transcript variants.
Gene ID 3769
Alternative Inward rectifier potassium channel 13; Inward rectifier K(+) channel Kir7.1; Potassium channel, inwardly rectifying subfamily J member 13
Others The antibody detects endogenous levels of IRK13 protein
Accession O60928
Observed Band(KD) 39

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