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INSL3 Polyclonal Antibody

INSL3 Polyclonal Antibody

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Specification

Product name INSL3 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human INSL3 protein at amino acid sequence of 10-50
Host Rabbit
Reactivity Human,Rat,Mouse,
Applications IHC,IF,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Insulin-like 3; Leydig insulin-like peptide; Ley-I-L; Relaxin-like factor

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background INSL3 encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that INSL3 may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in INSL3 may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. INSL3 (Insulin Like 3) is a Protein Coding gene. Diseases associated with INSL3 include Cryptorchidism and Testicular Cancer. Among its related pathways are G alpha(s) signalling events and Signaling by GPCR.
Gene ID 3640
Alternative Insulin-like 3; Leydig insulin-like peptide; Ley-I-L; Relaxin-like factor
Others The antibody detects endogenous levels of INSL3
Accession P51460

Image & description

Fig.1. Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200.

Fig.1. Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200.

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