|Product name||IL-8 Mouse Monoclonal Antibody (13F8)|
|Immunogen||Synthetic C-TERM Peptide of IL-8|
|Reactivity||Human, Mouse, Rat|
|Applications notes||Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:200).|
|Preparation method||The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen|
|Storage buffer||PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.|
|Storage instructions||Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.|
|Shipping||Gel pack with blue ice.|
|Precautions||The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.|
|Background||The protein encoded by CXCL8 (C-X-C motif chemokine ligand 8) is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. CXCL8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. CXCL8 and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.|
|Others||IL-8 protein detects endogenous levels of IL8.|
Fig.1. Immunohistochemical analysis of paraffin-embedded Human Lung Carrcinoma Tissue using IL-8 Mouse mAb diluted at 1:200.
Fig.2. Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using IL-8 Mouse mAb diluted at 1:200.