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IL-28Rα Polyclonal Antibody

IL-28Rα Polyclonal Antibody

Views(3) Publications(0) Catalog no(ABP52820)
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Specification

Product name IL-28Rα Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human IL-28Rα
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative IL28RA; IFNLR1; LICR2; Interleukin-28 receptor subunit alpha; IL-28 receptor subunit alpha; IL-28R-alpha; IL-28RA; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12; CRF2-12; Interferon lambda receptor 1; IFN-lambda receptor 1; IFN-lambda-R1; Likely interleukin or cytokine receptor 2; LICR2

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 57kD
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Interleukin-28 receptor subunit alpha encoded by IFNLR1 belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
Gene ID 163702
Alternative IL28RA; IFNLR1; LICR2; Interleukin-28 receptor subunit alpha; IL-28 receptor subunit alpha; IL-28R-alpha; IL-28RA; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12; CRF2-12; Interferon lambda receptor 1; IFN-lambda receptor 1; IFN-lambda-R1; Likely interleukin or cytokine receptor 2; LICR2
Others IL-28Rα Polyclonal Antibody detects endogenous levels of IL-28Rα protein.
Accession Q8IU57
Observed Band(KD) 57

Image & description

Fig. Western Blot analysis of extracts from K562 cells, using IL-28Rα Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig. Western Blot analysis of extracts from K562 cells, using IL-28Rα Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

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