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IFN-β Polyclonal Antibody

IFN-β Polyclonal Antibody

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Specification

Product name IFN-β Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human IFN-β protein at amino acid sequence of 91-140
Host Rabbit
Reactivity Human
Applications ELISA, IHC-P
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Alternative Interferon beta; IFN-beta; Fibroblast interferon

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol as stabilizer.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background IFNB1 encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by IFNB1 belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for IFNB1 display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.
Gene ID 3456
Alternative Interferon beta; IFN-beta; Fibroblast interferon
Others The antibody detects endogenous levels of IFN-β
Accession P01574

Image & description

Fig.1. Immunohistochemical analysis of paraffin-embedded human-placenta, antibody was diluted at 1:200.

Fig.1. Immunohistochemical analysis of paraffin-embedded human-placenta, antibody was diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-placenta, antibody was diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-placenta, antibody was diluted at 1:200.

Fig.3. Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200.

Fig.3. Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200.

Fig.4. Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200.

Fig.4. Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200.

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