Login Register
English
0

Cart

$ 0

Human CD38 protein, His tag (Animal-Free)

Human CD38 protein, His tag (Animal-Free)

Views(525) Publications(0) Catalog no(PRP2027)
Datasheet Print Share Email Share
  • Specification
  • FAQ
  • Publications(0)
  • Comments(0)

Specification

Product name Human CD38 protein, His tag (Animal-Free)
Sequence Amino acid sequence derived from human CD38 (P28907) (Val 43-Ile 300) was expressed with a 6 His tag at the C-terminus.
Protein length The recombinant human CD38 protein consists of 264 amino acids and predicts a molecular mass of 31 KD. It migrates as an approximately 42-45 KD band in SDS-PAGE under reducing conditions due to glycosylation.
Preparation method HEK293 Cells
Purity >95% as determined by SDS-PAGE.
Alternative ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1

Product Properties

Formulation Lyophilized from sterile PBS, pH 7.4.
Features & Benefits Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method.
Molecular weight 31 KD
Usage notes Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human CD38 protein using the buffer we provided not less than 100 µg/mL, which can then be further diluted to other aqueous solutions.
Storage instructions Lyophilized Human CD38 protein, His tag (Animal-Free)should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.103% HSA or BSA). Please prevent freeze-thaw cycles.
Shipping The product is shipped at ambient temperature.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)+ into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+, and ADP-ribose .CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells . Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic β  cells.
Gene ID 952
Alternative ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1
Accession P28907

Image & description

This product has been cited in0publications

Reviews

There are no reviews yet.

Be the first to review “Human CD38 protein, His tag (Animal-Free)”