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hnRNP L Polyclonal Antibody

hnRNP L Polyclonal Antibody

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Specification

Product name hnRNP L Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human hnRNP L at AA range: 30-110
Host Rabbit
Reactivity Human, Mouse
Applications ELISA, IF, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative HNRNPL; HNRPL; P/OKcl.14; Heterogeneous nuclear ribonucleoprotein L; hnRNP L

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID 3191
Alternative HNRNPL; HNRPL; P/OKcl.14; Heterogeneous nuclear ribonucleoprotein L; hnRNP L
Others hnRNP L Polyclonal Antibody detects endogenous levels of hnRNP L protein.
Accession P14866
Observed Band(KD) 60

Image & description

Fig.1. Western Blot analysis of various cells using hnRNP L Polyclonal Antibody.

Fig.1. Western Blot analysis of various cells using hnRNP L Polyclonal Antibody.

Fig.2. Western Blot analysis of HUVEC cells using hnRNP L Polyclonal Antibody.

Fig.2. Western Blot analysis of HUVEC cells using hnRNP L Polyclonal Antibody.

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