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hnRNP A2/B1 Polyclonal Antibody

hnRNP A2/B1 Polyclonal Antibody

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Specification

Product name hnRNP A2/B1 Polyclonal Antibody
Immunogen Synthesized peptide derived from the N-terminal region of human hnRNP A2/B1 at AA range: 1-80
Host Rabbit
Reactivity Human, Mouse
Applications ELISA, IF, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative HNRNPA2B1; HNRPA2B1; Heterogeneous nuclear ribonucleoproteins A2/B1; hnRNP A2/B1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background HNRNPA2B1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. Heterogeneous nuclear ribonucleoproteins A2/B1 encoded by HNRNPA2B1 has two repeats of quasi-RRM domains that bind to RNAs. HNRNPA2B1 has been described to generate two alternatively spliced transcript variants which encode different isoforms.
Gene ID 3181
Alternative HNRNPA2B1; HNRPA2B1; Heterogeneous nuclear ribonucleoproteins A2/B1; hnRNP A2/B1
Others hnRNP A2/B1 Polyclonal Antibody detects endogenous levels of hnRNP A2/B1 protein.
Accession P22626
Observed Band(KD) 36+38

Image & description

Fig. Western Blot analysis of various cells using hnRNP A2/B1 Polyclonal Antibody diluted at 1:1000.

Fig. Western Blot analysis of various cells using hnRNP A2/B1 Polyclonal Antibody diluted at 1:1000.

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