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HMG-2 Polyclonal Antibody

HMG-2 Polyclonal Antibody

Views(552) Publications(0) Catalog no(ABP51541)
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Specification

Product name HMG-2 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human HMG-2 at AA range: 100-180
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IF, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative HMGB2; HMG2; High mobility group protein B2; High mobility group protein 2; HMG-2

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that high mobility group protein B2 is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Gene ID 3148
Alternative HMGB2; HMG2; High mobility group protein B2; High mobility group protein 2; HMG-2
Others HMG-2 Polyclonal Antibody detects endogenous levels of HMG-2 protein.
Accession P26583
Observed Band(KD) 27

Image & description

Fig. Western Blot analysis of various cells using HMG-2 Polyclonal Antibody.

Fig. Western Blot analysis of various cells using HMG-2 Polyclonal Antibody.

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