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Histamine H2 Receptor Polyclonal Antibody

Histamine H2 Receptor Polyclonal Antibody

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Specification

Product name Histamine H2 Receptor Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human Histamine H2 Receptor at AA rangle: 100-180
Host Rabbit
Reactivity Human,Rat,Mouse,
Applications WB,IF,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative HRH2; Histamine H2 receptor; H2R; HH2R; Gastric receptor I

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 40kD
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for HRH2.
Gene ID 3274
Alternative HRH2; Histamine H2 receptor; H2R; HH2R; Gastric receptor I
Others Histamine H2 Receptor Polyclonal Antibody detects endogenous levels of Histamine H2 Receptor protein.
Accession P25021
Observed Band(KD) 40

Image & description

Fig. Western Blot analysis of 3T3 cells using Histamine H2 Receptor Polyclonal Antibody.

Fig. Western Blot analysis of 3T3 cells using Histamine H2 Receptor Polyclonal Antibody.

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