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GSK3α (phospho Ser21) Polyclonal Antibody

GSK3α (phospho Ser21) Polyclonal Antibody

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Specification

Product name GSK3α (phospho Ser21) Polyclonal Antibody
Immunogen Synthesized peptide derived from human GSK3α around the phosphorylation site of S21
Host Rabbit
Reactivity Human,Mouse,Rat
Applications WB,IHC,IF,IP,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;IP 2-5 ug:mg lysate;ELISA 1:20000;IF 1:50-200
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative GSK3A; Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 55kD
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background GSK3A encodes a multifunctional Ser/Thr protein kinase (glycogen synthase kinase 3 alpha) that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease.
Gene ID 2931
Alternative GSK3A; Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A
Others Phospho-GSK3α (S21) Polyclonal Antibody detects endogenous levels of GSK3α protein only when phosphorylated at S21.
Accession P49840
Observed Band(KD) 55

Image & description

Fig. Western Blot analysis of various cells using Phospho-GSK3α (S21) Polyclonal Antibody.

Fig. Western Blot analysis of various cells using Phospho-GSK3α (S21) Polyclonal Antibody.

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