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GRIK5 Polyclonal Antibody

GRIK5 Polyclonal Antibody

Views(3) Publications(0) Catalog no(ABP58713)
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Specification

Product name GRIK5 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human GRIK5 protein at amino acid sequence of 910-990
Host Rabbit
Reactivity Human,Rat,Mouse,
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Glutamate receptor ionotropic, kainate 5; GluK5; Excitatory amino acid receptor 2; EAA2; Glutamate receptor KA-2; KA2

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 107kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background GRIK5 encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternative splicing results in multiple transcript variants. GRIK5 (Glutamate Ionotropic Receptor Kainate Type Subunit 5) is a Protein Coding gene. Diseases associated with GRIK5 include Schizophrenia. Among its related pathways are Circadian entrainment and Presynaptic function of Kainate receptors.
Gene ID 2901
Alternative Glutamate receptor ionotropic, kainate 5; GluK5; Excitatory amino acid receptor 2; EAA2; Glutamate receptor KA-2; KA2
Others The antibody detects endogenous levels of GRIK5 protein
Accession Q16478
Observed Band(KD) 107

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