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GRB14 Polyclonal Antibody

GRB14 Polyclonal Antibody

Views(12) Publications(0) Catalog no(ABP51474)
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Specification

Product name GRB14 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human GRB14 at AA range: 50-130
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative GRB14; Growth factor receptor-bound protein 14; GRB14 adapter protein

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Growth factor receptor-bound protein 14 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. GRB14 encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Growth factor receptor-bound protein 14 likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. GRB14 may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants.
Gene ID 2888
Alternative GRB14; Growth factor receptor-bound protein 14; GRB14 adapter protein
Others GRB14 Polyclonal Antibody detects endogenous levels of GRB14 protein.
Accession Q14449
Observed Band(KD) 61

Image & description

Fig. Western Blot analysis of various cells using GRB14 Polyclonal Antibody.

Fig. Western Blot analysis of various cells using GRB14 Polyclonal Antibody.

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