Product Information

• Product name

  GM2/GD2 synthase Polyclonal Antibody

• Immunogen

  Synthesized peptide derived from the Internal region of human GM2/GD2 synthase at AA range: 250-330

• Host

  Rabbit

• Reactivity

  Human, Mouse, Rat

• Applications

  ELISA, WB

• Application notes

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

• Clonality

  Polyclonal

• Isotype

  Rabbit IgG

• Purification

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Fig. Western Blot analysis of various cells using GM2/GD2 synthase Polyclonal Antibody.

Product Properties

• Formulation

  Liquid solution

• Concentration

  1 mg/ml

• Storage buffer

  PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

• Storage instructions

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Shipping

  Gel pack with blue ice.

• Precautions

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

• Background

  GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. Beta-1,4 N-acetylgalactosaminyltransferase 1 is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. Beta-1,4 N-acetylgalactosaminyltransferase 1 catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene.

• Gene ID

  2583

• Alternative names

  B4GALNT1; GALGT; SIAT2; Beta-1; 4 N-acetylgalactosaminyltransferase 1; (N-acetylneuraminyl)-galactosylglucosylceramide; GM2/GD2 synthase; GalNAc-T

• Others

  GM2/GD2 synthase Polyclonal Antibody detects endogenous levels of GM2/GD2 synthase protein.

• Accession

  Q00973