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GCS-α-1 Polyclonal Antibody

GCS-α-1 Polyclonal Antibody

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Specification

Product name GCS-α-1 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human GCS-α-1
Host Rabbit
Reactivity Human,Mouse,Rat
Applications WB,CoIP,IHC,IF,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative GUCY1A3; GUC1A3; GUCSA3; GUCY1A1; Guanylate cyclase soluble subunit alpha-3; GCS-alpha-3; GCS-alpha-1; Soluble guanylate cyclase large subunit

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 77kD
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. Guanylate cyclase soluble subunit alpha-3 encoded by GUCY1A3 is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.
Gene ID 2982
Alternative GUCY1A3; GUC1A3; GUCSA3; GUCY1A1; Guanylate cyclase soluble subunit alpha-3; GCS-alpha-3; GCS-alpha-1; Soluble guanylate cyclase large subunit
Others GCS-α-1 Polyclonal Antibody detects endogenous levels of GCS-α-1 protein.
Accession Q02108
Observed Band(KD) 77

Image & description

Fig. Western Blot analysis of various cells using GCS-α-1 Polyclonal Antibody.

Fig. Western Blot analysis of various cells using GCS-α-1 Polyclonal Antibody.

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