| Product name | GAP-43 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from human GAP-43 around the non-phosphorylation site of S41 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC-P, WB |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Alternative | GAP43; Neuromodulin; Axonal membrane protein GAP-43; Growth-associated protein 43; Neural phosphoprotein B-50; pp46 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Storage buffer | PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Neuromodulin encoded by GAP43 has been termed a ‘growth' or ‘plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. Neuromodulin is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for GAP43. |
| Gene ID | 2596 |
| Alternative | GAP43; Neuromodulin; Axonal membrane protein GAP-43; Growth-associated protein 43; Neural phosphoprotein B-50; pp46 |
| Others | GAP-43 Polyclonal Antibody detects endogenous levels of GAP-43 protein. |
| Accession | P17677 |
| Observed Band(KD) | 43 |
Fig. 1. Western Blot analysis of various cells using GAP-43 Polyclonal Antibody diluted at 1:500.
Fig.2. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using GAP43 Antibody. The picture on the right is blocked with the synthesized peptide.
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