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Gab 1 (phospho Tyr627) Polyclonal Antibody

Gab 1 (phospho Tyr627) Polyclonal Antibody

Views(50) Publications(0) Catalog no(ABP50319)
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Specification

Product name Gab 1 (phospho Tyr627) Polyclonal Antibody
Immunogen Synthesized peptide derived from human Gab 1 around the phosphorylation site of Y627
Host Rabbit
Reactivity Human, Monkey, Mouse
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative GAB1; GRB2-associated-binding protein 1; GRB2-associated binder 1; Growth factor receptor bound protein 2-associated protein 1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background GRB2 associated binding protein 1 encoded by GAB1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for GAB1.
Gene ID 2549
Alternative GAB1; GRB2-associated-binding protein 1; GRB2-associated binder 1; Growth factor receptor bound protein 2-associated protein 1
Others Phospho-Gab 1 (Y627) Polyclonal Antibody detects endogenous levels of Gab 1 protein only when phosphorylated at Y627.
Accession Q13480
Observed Band(KD) 110

Image & description

Fig. Western Blot analysis of various cells using Phospho-Gab 1 (Y627) Polyclonal Antibody.

Fig. Western Blot analysis of various cells using Phospho-Gab 1 (Y627) Polyclonal Antibody.

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