| Product name | Frizzled-3 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human Frizzled-3 at AA range: 110-190 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | FZD3; Frizzled-3; Fz-3; hFz3 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 76kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | FZD3 is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of Frizzled-3 is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. FZD3 is a susceptibility locus for schizophrenia. |
| Gene ID | 7976 |
| Alternative | FZD3; Frizzled-3; Fz-3; hFz3 |
| Others | Frizzled-3 Polyclonal Antibody detects endogenous levels of Frizzled-3 protein. |
| Accession | Q9NPG1 |
| Observed Band(KD) | 76 |
Fig.1. Western Blot analysis of various cells using Frizzled-3 Polyclonal Antibody.
Fig.2. Western Blot analysis of RAW264.7 cells using Frizzled-3 Polyclonal Antibody.
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