| Product name | FKHRL1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human FKHRL1 protein |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:10000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 65kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | FOXO3 (Forkhead Box O3) is a Protein Coding gene. Diseases associated with FOXO3 include Rhabdomyosarcoma and Cervix Carcinoma. Among its related pathways are IL-2 Pathway and Longevity regulating pathway. FOXO3 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO3 likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of FOXO3 with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. |
| Gene ID | 2309 |
| Alternative | Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1 |
| Others | This antibody detects endogenous levels of FKHRL1. |
| Accession | O43524 |
| Observed Band(KD) | 65 |
Fig.1. Western blot analysis of various lysate, antibody was diluted at 1:1000. HRP, Goat Anti-Rabbit IgG (Cat #: A21020) secondary antibody was diluted at 1:20000.
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