| Product name | FHL2 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human FHL2 protein |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Four and a half LIM domains protein 2; FHL-2; LIM domain protein DRAL; Skeletal muscle LIM-protein 3; SLIM-3 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 30kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | FHL2 encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, FHL2 is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants encoding different isoforms have been identified. FHL2 (Four And A Half LIM Domains 2) is a Protein Coding gene. Diseases associated with FHL2 include Familial Isolated Dilated Cardiomyopathy and Rhabdomyosarcoma. Among its related pathways are Metabolism and Signaling events mediated by HDAC Class III. |
| Gene ID | 2274 |
| Alternative | Four and a half LIM domains protein 2; FHL-2; LIM domain protein DRAL; Skeletal muscle LIM-protein 3; SLIM-3 |
| Others | The antibody detects endogenous levels of FHL2 protein |
| Accession | Q14192 |
| Observed Band(KD) | 30 |
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