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ENT1 Polyclonal Antibody

ENT1 Polyclonal Antibody

Views(4) Publications(0) Catalog no(ABP52762)
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Specification

Product name ENT1 Polyclonal Antibody
Immunogen Synthesized peptide derived from the N-terminal region of human ENT1
Host Rabbit
Reactivity Human,Mouse,Rat
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative SLC29A1; ENT1; Equilibrative nucleoside transporter 1; Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; Equilibrative NBMPR-sensitive nucleoside transporter; Nucleoside transporter, es-type; Solute carrier family 29 member 1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 55kD
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background SLC29A1 is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
Gene ID 2030
Alternative SLC29A1; ENT1; Equilibrative nucleoside transporter 1; Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; Equilibrative NBMPR-sensitive nucleoside transporter; Nucleoside transporter, es-type; Solute carrier family 29 member 1
Others ENT1 Polyclonal Antibody detects endogenous levels of ENT1 protein.
Accession Q99808
Observed Band(KD) 55

Image & description

Fig. Western Blot analysis of extracts from Jurkat, K562,  NIH-3T3 cells, using ENT1 Polyclonal Antibody. Antibody was diluted at 1:2000. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig. Western Blot analysis of extracts from Jurkat, K562, NIH-3T3 cells, using ENT1 Polyclonal Antibody. Antibody was diluted at 1:2000. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

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