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ELAF Polyclonal Antibody

ELAF Polyclonal Antibody

Views(2) Publications(0) Catalog no(ABP58470)
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Specification

Product name ELAF Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human ELAF protein at amino acid sequence of 40-120
Host Rabbit
Reactivity Human
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Elafin; Elastase-specific inhibitor; ESI; Peptidase inhibitor 3; PI-3; Protease inhibitor WAP3 ; Skin-derived antileukoproteinase; WAP four-disulfide core domain protein 14

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 12kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background PI3 encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of PI3 is upgulated by bacterial lipopolysaccharides and cytokines.
Gene ID 5266
Alternative Elafin; Elastase-specific inhibitor; ESI; Peptidase inhibitor 3; PI-3; Protease inhibitor WAP3 ; Skin-derived antileukoproteinase; WAP four-disulfide core domain protein 14
Others The antibody detects endogenous levels of ELAF protein
Accession P19957
Observed Band(KD) 12

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