| Product name | Dok-2 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from human Dok-2 around the non-phosphorylation site of Y299 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | DOK2; Docking protein 2; Downstream of tyrosine kinase 2; p56(dok-2) |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 46kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Docking protein 2 encoded by DOK2 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 2 binds p120 (RasGAP) from CML cells. |
| Gene ID | 9046 |
| Alternative | DOK2; Docking protein 2; Downstream of tyrosine kinase 2; p56(dok-2) |
| Others | Dok-2 Polyclonal Antibody detects endogenous levels of Dok-2 protein. |
| Accession | O60496 |
| Observed Band(KD) | 46 |
Fig.1. Western Blot analysis of various cells using Dok-2 Polyclonal Antibody.
Fig.2. Western Blot analysis of COLO205 cells using Dok-2 Polyclonal Antibody.
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