|Product name||Desmin Polyclonal Antibody|
|Immunogen||Synthesized peptide derived from the C-terminal region of human Desmin at AA range: 390-470|
|Reactivity||Human, Mouse, Rat|
|Applications||ELISA, IF, IHC-P, WB|
|Applications notes||Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.|
|Preparation method||The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen|
|Molecular weight||55 KD|
|Storage buffer||PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.|
|Storage instructions||Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.|
|Shipping||Gel pack with blue ice.|
|Precautions||The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.|
|Background||DES encodes a muscle-specific class III intermediate filament. Homopolymers of desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in DES are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.|
|Others||Desmin Polyclonal Antibody detects endogenous levels of Desmin protein.|
Fig.1. Western Blot analysis of various cells using Desmin Polyclonal Antibody diluted at 1:2000.
Fig.2. Western Blot analysis of VEC cells using Desmin Polyclonal Antibody diluted at 1:2000.
Fig.3. The picture was kindly provided by our customer.