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CYP19A1 Polyclonal Antibody

CYP19A1 Polyclonal Antibody

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Specification

Product name CYP19A1 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human CYP19A1 at AA range: 190-270
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IF, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative CYP19A1; ARO1; CYAR; CYP19; Cytochrome P450 19A1; Aromatase; CYPXIX; Cytochrome P-450AROM; Estrogen synthase

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background CYP19A1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative splicing results in multiple transcript variants.
Gene ID 1588
Alternative CYP19A1; ARO1; CYAR; CYP19; Cytochrome P450 19A1; Aromatase; CYPXIX; Cytochrome P-450AROM; Estrogen synthase
Others CYP19A1 Polyclonal Antibody detects endogenous levels of CYP19A1 protein.
Accession P11511
Observed Band(KD) 53

Image & description

Fig.1. Western Blot analysis of various cells using CYP19A1 Polyclonal Antibody diluted at 1:1000.

Fig.1. Western Blot analysis of various cells using CYP19A1 Polyclonal Antibody diluted at 1:1000.

Fig.2. Western Blot analysis of 293 cells using CYP19A1 Polyclonal Antibody diluted at 1:1000.

Fig.2. Western Blot analysis of 293 cells using CYP19A1 Polyclonal Antibody diluted at 1:1000.

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