| Product name | Cyclin C (phospho Ser275) Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from human Cyclin C around the phosphorylation site of S275 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | CCNC; Cyclin-C; SRB11 homolog; hSRB11 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 33-37kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The protein encoded by CCNC (cyclin C) is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for CCNC. |
| Gene ID | 892 |
| Alternative | CCNC; Cyclin-C; SRB11 homolog; hSRB11 |
| Others | Phospho-Cyclin C (S275) Polyclonal Antibody detects endogenous levels of Cyclin C protein only when phosphorylated at S275. |
| Accession | P24863 |
| Observed Band(KD) | 33-37 |
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