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CSH1 Polyclonal Antibody

CSH1 Polyclonal Antibody

Views(76) Publications(0) Catalog no(ABP57546)
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Specification

Product name CSH1 Polyclonal Antibody
Immunogen Synthetic peptide from human protein at AA range: 161-210
Host Rabbit
Reactivity Human
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:10000), ELISA (1:10000).
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Alternative CSH1; CSH2

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The protein encoded by CSH1 (chorionic somatomammotropin hormone 1) is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. CSH1 is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in CSH1 result in placental lactogen deficiency and Silver-Russell syndrome.
Gene ID 1442
Alternative CSH1; CSH2
Others The antibody detects endogenous CSH1 protein.
Accession P01243
Observed Band(KD) 25

Image & description

Fig. Western Blot analysis of Mouse-brain cells using Antibody diluted at 1:800. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig. Western Blot analysis of Mouse-brain cells using Antibody diluted at 1:800. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

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