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Crk-L Polyclonal Antibody

Crk-L Polyclonal Antibody

Views(82) Publications(0) Catalog no(ABP51054)
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Specification

Product name Crk-L Polyclonal Antibody
Immunogen Synthesized peptide derived from human Crk-L around the non-phosphorylation site of Y207
Host Rabbit
Reactivity Human, Monkey, Mouse, Rat
Applications ELISA, IF, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative CRKL; Crk-like protein

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background CRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Gene ID 1399
Alternative CRKL; Crk-like protein
Others Crk-L Polyclonal Antibody detects endogenous levels of Crk-L protein.
Accession P46109
Observed Band(KD) 39

Image & description

Fig. Western Blot analysis of various cells using Crk-L Polyclonal Antibody.

Fig. Western Blot analysis of various cells using Crk-L Polyclonal Antibody.

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