| Product name | Collagen II Mouse Monoclonal Antibody (7F9) |
| Immunogen | Synthetic Peptide of Collagen II |
| Host | Mouse |
| Reactivity | Human,Mouse,Rat |
| Applications | IHC,IF |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300;IF 1:50-200 |
| Clonality | Monoclonal |
| Preparation method | The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Collagen alpha-1(II) chain; Alpha-1 type II collagen |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 142kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | COL2A1 (collagen type II alpha 1 chain) encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in COL2A1 are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for COL2A1. |
| Gene ID | 1280 |
| Alternative | Collagen alpha-1(II) chain; Alpha-1 type II collagen |
| Others | The antibody detects endogenous Collagen II protein . |
| Accession | P02458 |
| Observed Band(KD) | 142 |
Fig.1. Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using Collagen II Mouse mAb diluted at 1:500.
Fig.2. Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using Collagen II Mouse mAb diluted at 1:500.
Fig.3. Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma Tissue using Collagen II Mouse mAb diluted at 1:500.
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