| Product name | CMTM8 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human CMTM8 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | CMTM8; CKLFSF8; CKLF-like MARVEL transmembrane domain-containing protein 8; Chemokine-like factor superfamily member 8 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 20kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | CMTM8 (CKLF like MARVEL transmembrane domain containing 8) belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. CMTM8 is one of several chemokine-like factor genes located in a cluster on chromosome 3. CMTM8 acts as a tumor suppressor, and plays a role in regulating the migration of tumor cells. The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Gene ID | 152189 |
| Alternative | CMTM8; CKLFSF8; CKLF-like MARVEL transmembrane domain-containing protein 8; Chemokine-like factor superfamily member 8 |
| Others | CMTM8 Polyclonal Antibody detects endogenous levels of CMTM8 protein. |
| Accession | Q8IZV2 |
| Observed Band(KD) | 20 |
Fig.1. Western blot analysis of hela lysis using CMTM8 antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.
Fig.2. Immunohistochemical analysis of paraffin-embedded human-tonsils, antibody was diluted at 1:200.
Fig.3. Immunohistochemical analysis of paraffin-embedded human-tonsils, antibody was diluted at 1:200.
Fig.4. Immunohistochemical analysis of paraffin-embedded human-tonsils2, antibody was diluted at 1:100.
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