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Cleaved-Thrombin R (S42) Polyclonal Antibody

Cleaved-Thrombin R (S42) Polyclonal Antibody

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Specification

Product name Cleaved-Thrombin R (S42) Polyclonal Antibody
Immunogen Synthesized peptide derived from the N-terminal region of human Thrombin R at AA rangle: 40-120
Host Rabbit
Reactivity Human
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative F2R; CF2R; PAR1; TR; Proteinase-activated receptor 1; PAR-1; Coagulation factor II receptor; Thrombin receptor

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants.
Gene ID 2149
Alternative F2R; CF2R; PAR1; TR; Proteinase-activated receptor 1; PAR-1; Coagulation factor II receptor; Thrombin receptor
Others Cleaved-Thrombin R (S42) Polyclonal Antibody detects endogenous levels of fragment of activated Thrombin R protein resulting from cleavage adjacent to S42.
Accession P25116
Observed Band(KD) 46

Image & description

Fig. Western Blot analysis of Jurkat cells using Cleaved-Thrombin R (S42) Polyclonal Antibody.

Fig. Western Blot analysis of Jurkat cells using Cleaved-Thrombin R (S42) Polyclonal Antibody.

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