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Cleaved-Cathepsin L2 (L114) Polyclonal Antibody

Cleaved-Cathepsin L2 (L114) Polyclonal Antibody

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Specification

Product name Cleaved-Cathepsin L2 (L114) Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human Cathepsin L2 at AA range: 70-150
Host Rabbit
Reactivity Human, Monkey
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative CTSL2; CATL2; CTSU; CTSV; Cathepsin L2; Cathepsin U; Cathepsin V

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Cathepsin V encoded by CTSV, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. CTSV is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for CTSV in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified.
Gene ID 1515
Alternative CTSL2; CATL2; CTSU; CTSV; Cathepsin L2; Cathepsin U; Cathepsin V
Others Cleaved-Cathepsin L2 (L114) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin L2 protein resulting from cleavage adjacent to L114.
Accession O60911
Observed Band(KD) 37

Image & description

Fig. Western Blot analysis of various cells using Cleaved-Cathepsin L2 (L114) Polyclonal Antibody.

Fig. Western Blot analysis of various cells using Cleaved-Cathepsin L2 (L114) Polyclonal Antibody.

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