| Product name | Cleaved-Cathepsin L2 (L114) Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human Cathepsin L2 at AA range: 70-150 |
| Host | Rabbit |
| Reactivity | Human,Monkey |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | CTSL2; CATL2; CTSU; CTSV; Cathepsin L2; Cathepsin U; Cathepsin V |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 37kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Cathepsin V encoded by CTSV, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. CTSV is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for CTSV in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. |
| Gene ID | 1515 |
| Alternative | CTSL2; CATL2; CTSU; CTSV; Cathepsin L2; Cathepsin U; Cathepsin V |
| Others | Cleaved-Cathepsin L2 (L114) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin L2 protein resulting from cleavage adjacent to L114. |
| Accession | O60911 |
| Observed Band(KD) | 37 |
Fig. Western Blot analysis of various cells using Cleaved-Cathepsin L2 (L114) Polyclonal Antibody.
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