| Product name | CLC-KA Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the C-terminal region of human CLC-KA at AA range: 550-630 |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse, |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | CLCNKA; Chloride channel protein ClC-Ka; Chloride channel Ka; ClC-K1 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 75kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | CLCNKA is a member of the CLC family of voltage-gated chloride channels. The encoded protein (chloride voltage-gated channel Ka) is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for CLCNKA. |
| Gene ID | 1187 |
| Alternative | CLCNKA; Chloride channel protein ClC-Ka; Chloride channel Ka; ClC-K1 |
| Others | CLC-KA Polyclonal Antibody detects endogenous levels of CLC-KA protein. |
| Accession | P51800 |
| Observed Band(KD) | 75 |
Fig. Western Blot analysis of various cells using CLC-KA Polyclonal Antibody.
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