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Claudin-7 (phospho Tyr210) Polyclonal Antibody

Claudin-7 (phospho Tyr210) Polyclonal Antibody

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Specification

Product name Claudin-7 (phospho Tyr210) Polyclonal Antibody
Immunogen Synthesized peptide derived from human Claudin-7 around the phosphorylation site of Y210
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative CLDN7; CEPTRL2; CPETRL2; Claudin-7; CLDN-7

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background CLDN7 encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
Gene ID 1366
Alternative CLDN7; CEPTRL2; CPETRL2; Claudin-7; CLDN-7
Others Phospho-Claudin-7 (Y210) Polyclonal Antibody detects endogenous levels of Claudin-7 protein only when phosphorylated at Y210.
Accession O95471
Observed Band(KD) 32

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