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Claudin-4 Polyclonal Antibody

Claudin-4 Polyclonal Antibody

Views(63) Publications(1) Catalog no(ABP50989)
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Specification

Product name Claudin-4 Polyclonal Antibody
Immunogen Synthesized peptide derived from the C-terminal region of human Claudin-4 at AA range: 130-210
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IF, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative CLDN4; CPER; CPETR1; WBSCR8; Claudin-4; Clostridium perfringens enterotoxin receptor; CPE-R; CPE-receptor; Williams-Beuren syndrome chromosomal region 8 protein

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Claudin 4 encoded by this intronless gene (CLDN4) belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
Gene ID 1364
Alternative CLDN4; CPER; CPETR1; WBSCR8; Claudin-4; Clostridium perfringens enterotoxin receptor; CPE-R; CPE-receptor; Williams-Beuren syndrome chromosomal region 8 protein
Others Claudin-4 Polyclonal Antibody detects endogenous levels of Claudin-4 protein.
Accession O14493
Observed Band(KD) 22

Image & description

Fig.1. Western Blot analysis of various cells using Claudin-4 Polyclonal Antibody diluted at 1:2000.

Fig.1. Western Blot analysis of various cells using Claudin-4 Polyclonal Antibody diluted at 1:2000.

Fig.2. Western Blot analysis of HeLa cells using Claudin-4 Polyclonal Antibody diluted at 1:2000.

Fig.2. Western Blot analysis of HeLa cells using Claudin-4 Polyclonal Antibody diluted at 1:2000.

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