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CD89 Polyclonal Antibody

CD89 Polyclonal Antibody

Views(70) Publications(0) Catalog no(ABP53299)
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Specification

Product name CD89 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human CD89
Host Rabbit
Reactivity Human
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative FCAR; CD89; Immunoglobulin alpha Fc receptor; IgA Fc receptor; CD89

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background FCAR is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID 2204
Alternative FCAR; CD89; Immunoglobulin alpha Fc receptor; IgA Fc receptor; CD89
Others CD89 Polyclonal Antibody detects endogenous levels of CD89 protein.
Accession P24071
Observed Band(KD) 32

Image & description

Fig.1. Western Blot analysis of NIH-3T3 cells using CD89 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.1. Western Blot analysis of NIH-3T3 cells using CD89 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-tonsils, antibody was diluted at 1:100.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-tonsils, antibody was diluted at 1:100.

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