| Product name | CD68 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human CD68 |
| Host | Rabbit |
| Reactivity | Human,Rat |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | CD68; Macrosialin; Gp110; CD68 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 37kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | CD68 encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. |
| Gene ID | 968 |
| Alternative | CD68; Macrosialin; Gp110; CD68 |
| Others | CD68 Polyclonal Antibody detects endogenous levels of CD68 protein. |
| Accession | P34810 |
| Observed Band(KD) | 37 |
Fig.1. Western Blot analysis of Mouse spleen cells using CD68 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.
Fig.2. Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:100.
Fig.3. Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:100.
Fig.4. Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100.
Fig.5. Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100.
Fig.6. Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100.
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