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CD1E Polyclonal Antibody

CD1E Polyclonal Antibody

Views(17) Publications(0) Catalog no(ABP52971)
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Specification

Product name CD1E Polyclonal Antibody
Immunogen Synthesized peptide derived from the C-terminal region of human CD1E
Host Rabbit
Reactivity Human
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative CD1E; T-cell surface glycoprotein CD1e, membrane-associated; hCD1e; R2G1; CD1e

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background CD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found; however, their biological validity has not been determined.
Gene ID 913
Alternative CD1E; T-cell surface glycoprotein CD1e, membrane-associated; hCD1e; R2G1; CD1e
Others CD1E Polyclonal Antibody detects endogenous levels of CD1E protein.
Accession P15812
Observed Band(KD) 42

Image & description

Fig.1. Western Blot analysis of K562 cells using CD1E Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.1. Western Blot analysis of K562 cells using CD1E Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:100.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:100.

Fig.3. Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:100.

Fig.3. Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:100.

Fig.4. Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:100.

Fig.4. Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:100.

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