Login Register
English
0

Cart

$ 0

Btk (phospho Tyr551) Polyclonal Antibody

Btk (phospho Tyr551) Polyclonal Antibody

Views(51) Publications(0) Catalog no(ABP50424)
Datasheet Print Share Email Share
  • Specification
  • FAQ
  • Publications(0)
  • Comments(0)

Specification

Product name Btk (phospho Tyr551) Polyclonal Antibody
Immunogen Synthesized peptide derived from human Btk around the phosphorylation site of Y551
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative BTK; AGMX1; ATK; BPK; Tyrosine-protein kinase BTK; Agammaglobulinaemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinase

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Bruton tyrosine kinase encoded by BTK plays a crucial role in B-cell development. Mutations in BTK cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID 695
Alternative BTK; AGMX1; ATK; BPK; Tyrosine-protein kinase BTK; Agammaglobulinaemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinase
Others Phospho-Btk (Y551) Polyclonal Antibody detects endogenous levels of Btk protein only when phosphorylated at Y551.
Accession Q06187
Observed Band(KD) 80

Image & description

Fig.1. Western Blot analysis of various cells using Phospho-Btk (Y551) Polyclonal Antibody.

Fig.1. Western Blot analysis of various cells using Phospho-Btk (Y551) Polyclonal Antibody.

Fig.2. Western Blot analysis of HeLa cells using Phospho-Btk (Y551) Polyclonal Antibody.

Fig.2. Western Blot analysis of HeLa cells using Phospho-Btk (Y551) Polyclonal Antibody.

This product has been cited in0publications

Reviews

There are no reviews yet.

Be the first to review “Btk (phospho Tyr551) Polyclonal Antibody”