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Bradykinin B1 R Polyclonal Antibody

Bradykinin B1 R Polyclonal Antibody

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Product name Bradykinin B1 R Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human Bradykinin B1 R at AA range: 180-260
Host Rabbit
Reactivity Human
Applications ELISA, IF, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative BDKRB1; BRADYB1; B1 bradykinin receptor; B1R; BK-1 receptor

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by BDKRB1 (bradykinin receptor B1) is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for BDKRB1.
Gene ID 623
Alternative BDKRB1; BRADYB1; B1 bradykinin receptor; B1R; BK-1 receptor
Others Bradykinin B1 R Polyclonal Antibody detects endogenous levels of Bradykinin B1 R protein.
Accession P46663
Observed Band(KD) 40

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