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BMP-9 Polyclonal Antibody

BMP-9 Polyclonal Antibody

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Specification

Product name BMP-9 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human BMP-9 protein at amino acid sequence of 371-420
Host Rabbit
Reactivity Human, Mouse
Applications ELISA, IHC-P
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Alternative Growth/differentiation factor 2; GDF-2; Bone morphogenetic protein 9; BMP-9

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol as stabilizer.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background GDF2 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in GDF2 are associated with hereditary hemorrhagic telangiectasia.
Gene ID 2658
Alternative Growth/differentiation factor 2; GDF-2; Bone morphogenetic protein 9; BMP-9
Others The antibody detects endogenous levels of BMP-9
Accession Q9UK05

Image & description

Fig.1. Immunohistochemical analysis of paraffin-embedded human-liver-cancer, antibody was diluted at 1:200.

Fig.1. Immunohistochemical analysis of paraffin-embedded human-liver-cancer, antibody was diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-liver-cancer, antibody was diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-liver-cancer, antibody was diluted at 1:200.

Fig.3. Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200.

Fig.3. Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200.

Fig.4. Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200.

Fig.4. Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200.

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