| Product name | BMP-9 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human BMP-9 protein at amino acid sequence of 371-420 |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC-P |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000). |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
| Alternative | Growth/differentiation factor 2; GDF-2; Bone morphogenetic protein 9; BMP-9 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Storage buffer | PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol as stabilizer. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | GDF2 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in GDF2 are associated with hereditary hemorrhagic telangiectasia. |
| Gene ID | 2658 |
| Alternative | Growth/differentiation factor 2; GDF-2; Bone morphogenetic protein 9; BMP-9 |
| Others | The antibody detects endogenous levels of BMP-9 |
| Accession | Q9UK05 |
Fig.1. Immunohistochemical analysis of paraffin-embedded human-liver-cancer, antibody was diluted at 1:200.
Fig.2. Immunohistochemical analysis of paraffin-embedded human-liver-cancer, antibody was diluted at 1:200.
Fig.3. Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200.
Fig.4. Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200.
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1.The species of antibody reactivity should be the sample species that can be matched normally after Abbkine R&D experts have passed strict scientific verification. If your sample is not within the range of reactivity, in order to improve the efficiency and results of your experiment, it is not suggested to try other species. Otherwise, it may lead to sample mismatch and affect the effect of your experiment.
2.Please aliquot the antibody received as soon as possible and store it at -20℃, avoid repeated freezing and thawing, and use it within one year.
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