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Bcl-2 (phospho Thr69) Polyclonal Antibody

Bcl-2 (phospho Thr69) Polyclonal Antibody

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Specification

Product name Bcl-2 (phospho Thr69) Polyclonal Antibody
Immunogen Synthesized peptide derived from human Bcl-2 around the phosphorylation site of T69
Host Rabbit
Reactivity Human
Applications ELISA, IF, IHC-P
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative BCL2; Apoptosis regulator Bcl-2

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background BCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
Gene ID 596
Alternative BCL2; Apoptosis regulator Bcl-2
Others Phospho-Bcl-2 (T69) Polyclonal Antibody detects endogenous levels of Bcl-2 protein only when phosphorylated at T69.
Accession P10415

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