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APOBEC3A Polyclonal Antibody

APOBEC3A Polyclonal Antibody

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Specification

Product name APOBEC3A Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human APOBEC3A at AA rangle: 40-120
Host Rabbit
Reactivity Human
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative APOBEC3A; Probable DNA dC->dU-editing enzyme APOBEC-3A; Phorbolin-1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background APOBEC3A is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID 200315
Alternative APOBEC3A; Probable DNA dC->dU-editing enzyme APOBEC-3A; Phorbolin-1
Others APOBEC3A Polyclonal Antibody detects endogenous levels of APOBEC3A protein.
Accession P31941

Image & description

Fig. Western Blot analysis of Jurkat cells using APOBEC3A Polyclonal Antibody.

Fig. Western Blot analysis of Jurkat cells using APOBEC3A Polyclonal Antibody.

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