| Product name | Amphiregulin Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human Amphiregulin |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse, |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | AREG; SDGF; AREGB; Amphiregulin; AR; Colorectum cell-derived growth factor; CRDGF |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 17kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The amphiregulin encoded by AREG is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. |
| Gene ID | 374/727738 |
| Alternative | AREG; SDGF; AREGB; Amphiregulin; AR; Colorectum cell-derived growth factor; CRDGF |
| Others | Amphiregulin Polyclonal Antibody detects endogenous levels of Amphiregulin protein. |
| Accession | P15514 |
Fig. Western Blot analysis of HBE cells using Amphiregulin Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.
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