Unlock Apoptosis Analysis Precision: Abbkine KTA0002 Annexin V-AbFluor™ 488/PI Detection Kit – Your Go-To Research Essential

Apoptosis, the programmed cell death, is a cornerstone of biological processes—from development and tissue homeostasis to disease pathogenesis and drug response. Accurate discrimination of intact cells, early apoptotic, and late apoptotic/necrotic cells is critical for advancing research in cell biology, oncology, pharmacology, and immunology. For researchers seeking a reliable, user-friendly, and high-performance solution, the Abbkine Annexin V-AbFluor™ 488/PI Apoptosis Detection Kit (Catalog No.: KTA0002) stands out as a game-changing tool that redefines apoptosis analysis standards—now available with exclusive promotional offers.

The Science Behind Unmatched Apoptosis Discrimination

At the core of the KTA0002 kit lies a gold-standard dual-staining technology, leveraging the unique properties of Annexin V-AbFluor™ 488 and Propidium Iodide (PI) to deliver precise cell classification.

Annexin V, a calcium-dependent phospholipid-binding protein, exhibits high affinity for phosphatidylserine (PS)—a phospholipid that translocates from the inner to the outer leaflet of the cell membrane during the early stages of apoptosis. Conjugated with AbFluor™ 488, a bright, photostable fluorophore, Annexin V enables specific labeling of early apoptotic cells with green fluorescence. Meanwhile, PI—a membrane-impermeable nucleic acid dye—only penetrates cells with compromised membranes (late apoptotic or necrotic cells), emitting red fluorescence upon binding to DNA.

This synergistic dual-staining system allows clear differentiation of three cell populations:

• Intact cells (Annexin V⁻/PI⁻): No green or red fluorescence.
• Early apoptotic cells (Annexin V⁺/PI⁻): Positive for green fluorescence only.
• Late apoptotic/necrotic cells (Annexin V⁺/PI⁺): Positive for both green and red fluorescence.

Unlike low-quality kits prone to nonspecific binding or weak signal intensity, Abbkine optimizes the KTA0002 formulation for minimal background noise and maximum signal-to-noise ratio. Each component—from the fluorophore-conjugated Annexin V to the PI solution and binding buffer—undergoes strict quality control to ensure batch-to-batch consistency, empowering researchers to generate reproducible data that stands up to rigorous peer review.

Key Features That Elevate Your Apoptosis Research

• Precise Cell Population Discrimination: Reliably distinguishes intact, early apoptotic, and late apoptotic/necrotic cells—eliminating ambiguity in results.
• Bright, Photostable Fluorophores: AbFluor™ 488 offers exceptional brightness and photostability, ensuring clear signal detection even in long-term imaging or high-throughput analysis.
• User-Friendly Protocol: Streamlined steps require minimal hands-on time (30 minutes total incubation) and no specialized technical expertise. Compatible with both flow cytometry and fluorescence microscopy—adapting to your lab’s workflow.
• Broad Sample Compatibility: Works seamlessly with adherent cells, suspension cells, and primary cells from humans, mice, rats, and other model organisms—flexible for diverse research needs.
• Stable & Reliable Formulation: Components are optimized for long-term storage (at -20°C) without loss of activity, reducing reagent waste and ensuring consistent performance.
• Exceptional Value with Promotion: Priced at just $139 for 50 tests, the kit delivers unbeatable 性价比 (cost-effectiveness) for routine experiments or high-throughput drug screening—enhanced by exclusive promotional offers.

Versatile Applications Across Research Domains

The Abbkine KTA0002 kit is not just a reagent—it’s a versatile solution that empowers breakthroughs across multiple research fields:

• Oncology Research: Evaluate drug-induced apoptosis in cancer cell lines, assess tumor cell response to chemotherapy/radiotherapy, or study apoptotic pathways in tumor progression.
• Drug Discovery & Development: High-throughput screening of novel compounds (e.g., anticancer drugs, neuroprotective agents) for their ability to induce or inhibit apoptosis.
• Cell Biology & Immunology: Investigate apoptosis in immune cells (e.g., T cells, B cells) during inflammation, infection, or immune regulation; study developmental apoptosis in embryonic cells.
• Neurobiology: Analyze neuronal apoptosis in neurodegenerative diseases (e.g., Alzheimer’s, Parkinson’s) or in response to neurotoxins.
• Toxicology Studies: Assess cytotoxicity of environmental toxins, industrial chemicals, or nanoparticles by monitoring apoptotic/necrotic cell populations.

Trusted by Researchers Worldwide

“For years, our lab has relied on Abbkine’s apoptosis detection kits, and KTA0002 has become our top choice. The dual-staining system consistently delivers crisp, unambiguous results—whether we’re using flow cytometry for high-throughput analysis or fluorescence microscopy for imaging. At $139 for 50 tests, it’s also one of the most cost-effective options on the market, which is a game-changer for our large-scale drug screening projects. Highly recommend to any researcher working on apoptosis!” — Dr. Sarah Chen, Lead Investigator, Cellular and Molecular Biology Lab, Stanford University

Grab the Promotional Offer & Elevate Your Research Today

Don’t settle for subpar apoptosis assays that compromise data quality or drain your budget. The Abbkine Annexin V-AbFluor™ 488/PI Apoptosis Detection Kit (Catalog No.: KTA0002) combines precision, ease of use, and unbeatable value—now with exclusive promotional benefits—to help you unlock new insights in your research.

To learn more about the promotion, review technical specifications, or place an order, visit the official product page: https://www.abbkine.com/?s_type=productsearch&s=KTA0002

Join thousands of researchers who trust Abbkine for high-quality reagents that turn research challenges into discoveries. Master apoptosis analysis with KTA0002—your key to reliable, impactful data.

Abbkine: Empowering Life Science Research, One Reagent at a Time.