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Total 6 Pages/ 60 Results
  • New

    Human FGF-5 Protein, His tag (Animal-Free)

    Views(54) Publications(0) Catalog No(PRP1009)

    Descriptions:Fibroblast Growth Factors-5 (FGF-5) is a 29.6 kDa member of the fibroblast Growth Factors with 268 amino acid residues. FGF-5 have an important role in the regulation of cell proliferation and cell differentiation. In physiological function, FGF5 is a crucial regulator of hair growth in humans.

    Applications:His tag

    Tags:FGF-5

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    Mouse GDNF Protein, His tag (Animal-Free)

    Views(54) Publications(0) Catalog No(PRP1107)

    Descriptions:Glial Cell Line-derived Neurotrophic Factor (GDNF) is the neurotrophic factor, belonging to the GDNF family of ligands (GFL) and identifying as a therapeutic candidate in Parkinson's disease.GDNF is a 23.7 kDa protein containing 211 residues that plays a critical role in promoting the survival and differentiation of midbrain dopamine neurons. Besides, GDNF is revealed to facilitate the development of peripheral tissues such as kidney, pancreas and lung. Additionally, as a member of GFL, GDNF also takes part in the progression of tumor.

    Applications:His tag

    Tags:GDNF

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    Human BMP-10 Protein, His tag (Animal-Free)

    Views(53) Publications(0) Catalog No(PRP1202)

    Descriptions:Bone Morphogenetic Protein-10 (BMP-10) is an extracellular multifunctional signaling cytokine that is also a member of the TGFβ family. BMP-10 can bind with TGFβ receptor and is involved in SMAD protein signal transduction. The functions related to bone generation can induce bone and cartilage formation. Different from other family members, BMP-10 is a novel protein involved in the heart's trabeculation.

    Applications:His tag

    Tags:BMP-10

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    Mouse IL-9 Protein, His tag (Animal-Free)

    Views(53) Publications(0) Catalog No(PRP1112)

    Descriptions:Interleukin 9, also known as IL-9, is a pleiotropic cytokine (cell signalling molecule) belonging to the group of interleukins. IL-9 is produced by variety of cells like mast cells, NKT cells, Th2, Th17, Treg, ILC2, and Th9 cells in different amounts. Among them, Th9 cells are regarded as the major CD4+ T cells that produce IL-9.

    Applications:His tag

    Tags:IL-9

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    Mouse CXCL3 Protein, His tag (Animal-Free)

    Views(53) Publications(0) Catalog No(PRP1117)

    Descriptions:C-X-C motif chemokine 3 (CXCL3) also named Growth-regulated oncogene gamma (GROγ), which is a chemokine of the intercrine alpha family. CXCL3 is a 8 kDa protein containing 73 amino acid residues. During inflammation, CXCL3 is activated by the TNF and IL-1 which mediates the monocytes migration and adhesion by targeting the CXCR2. CXCL3 activates the JNK activity which induce the cell differentiation.

    Applications:His tag

    Tags:CXCL3

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    Mouse IL-36α Protein, His tag (Animal-Free)

    Views(52) Publications(0) Catalog No(PRP1115)

    Descriptions:Interleukin 36 alpha (IL-36 alpha) is a 17.76 kDa cytokine with 160 amino acid residues. IL-36 alpha is an IL-1 family member, which binds to the Interleukin-1 receptor and is expressed in the lung, stomach, and placenta. IL-36 alpha is critical in inflammatory responses and stimulates the production of proinflammatory cytokines, such as IL-12, IL-1β, IL-6, and TNF-α. It also induces the generation of IFNγ, IL-4, and IL-17 in CD4+ T cells.

    Applications:His tag

    Tags:IL-36α

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    Human IFN-Ω Protein, His tag (Animal-Free)

    Views(52) Publications(0) Catalog No(PRP1125)

    Descriptions:Interferon Omega (IFN-ω) is a 20.12 kDa member of type I IFN family with 173 amino acid residues. IL-28B is expressed by epithelial tissues. IFN-ω with antiviral, antitumor activity and regulating the innate immune response. Able to activate P13K/Akt signaling pathway via binding its receptor IFNAR in cells.

    Applications:His tag

    Tags:IFN-Ω

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    Human IL-17D Protein, His tag (Animal-Free)

    Views(52) Publications(0) Catalog No(PRP1130)

    Descriptions:Interleukin 17D (IL-17D) is a 20.2 kDa member of IL-17 family with 185 amino acid residues. IL-17D is expressed by skeletal muscle, brain, adipose tissue, heart, lung, pancreas and secreted to blood. IL-17D can stimulate the production of cytokines such as IL-6, IL-8, GM-CSF, and stimulate local infiltration and proliferation of leukocytes.

    Applications:His tag

    Tags:IL-17D

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  • New

    Human TNF-β Protein, His tag (Animal-Free)

    Views(52) Publications(0) Catalog No(PRP1123)

    Descriptions:Human TNF beta (Lymphotoxin-alpha) is a 22 kDa cytokine with 205 amino acid residues. TNF beta belongs to tumor necrosis factor (TNF) superfamily as TNF alpha. Binding to lymphotoxin-β receptor (LtβR), canonical and non-canonical NF-κB signal pathway will be activated. TNF beta is related to apoptosis and inflammatory signals

    Applications:His tag

    Tags:TNF-β

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  • New

    Human Galectin-2 Protein, His tag (Animal-Free)

    Views(52) Publications(0) Catalog No(PRP1215)

    Descriptions:Galectin-2 (Gal-2) is a lectin family member and structurally closely related to galectin-1. It contains one carbohydrate recognition domain (CRD), responsible for β-galactoside binding, and is biologically active as homodimers. Galectin-2 serves as a proapoptotic effector for activated T cells through caspase-3 signaling. Moreover, galectin-2 has emerged as a crucial factor in driving the macrophage to CD40-positive M1 polarization, leading to arteriogenesis attenuation and collateral arteries remodeling.

    Applications:His tag

    Tags:Galectin-2

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